Senior Scientist – Infectious Disease Research

25 سبتمبر، 2022

0 2 3 دقائق

الوصف الوظيفي

SENIOR SCIENTIST – INFECTIOUS DISEASE RESEARCH
General Summary
The Senior Scientist functions as a subject matter expert within the organization and has oversight of the scientific elements to ensure successful completion and/or implementation. This position analyzes and reports results for publication or to sponsor; provides instruction to other members of the project team; and collaborates with other senior members of the staff on projects/research. Highest level of individual contributor. Knowledgeable of emerging trends and may contribute to and influence best practice within discipline.
Essential Duties & Responsibilities

Perform role of Study Director (SD) and Scientific Subject Matter Expert (SME) on infectious disease projects.
In vivo and in vitro experimental study design for vaccines and therapeutics and interact with clients.
Directs in vivo and/or in vitro studies and oversees assay development/validation and other experiments conducted in Operations.
Partners with Business Development, Project Management, and Proposals to ensure successful client engagement, proposal development, study execution, and deliverables upon study completion.
In collaboration with the marketing support function in CRO Services, responsible for new pipeline development under IR&D funding.
Within defined policies and procedures, provides resolution to complex scientific problems within a specified program.
Participates in all required Good Laboratory Practice (GLP) training.
Works closely with Study Coordinator and/or Project Manager as Technical SME on assigned projects and will interface with client's scientific staff as appropriate.
Develops assays; completes study designs for infectious disease In Vitro and/or In Vivo studies.
Oversees and serves as a technical advisor for lab operations to execute assay development and validation experiments.
Writes study protocols and validation plans.
Supports troubleshooting assay issues in validation and sample analysis.
Participates in proposal generation and performs scientific/technical review.
Follows GLP practices to ensure all experimental data, including observations of unanticipated responses are accurately recorded and verified.
Ensures compliance to all regulatory and safety requirements for work with select agents.
Observes appropriate safety and study requirements by reading, understanding, and following Standard Operating Procedures (SOP), GLP requirements, and study protocols.
Accountable for some level of revenue generation.
Data analysis and prepare study reports

Requirements/Minimum Qualifications

PhD in life sciences discipline plus at least 4 years' relevant experience.
Proven track record of leading large commercial or government proposal generation and securement of funding.
Has advanced the field of knowledge in his/her specialty. Work directly impacts the present or future of the organization in significant ways.
Broad experience in iinfectious disease research with in vitro and in vivo models is preferred.
Immunogenicity and efficacy testing in Animal models such as mice, ferrets, hamsters, monkeys
Presentation and statistical analysis of data
Proficient in assay development/qualification and directing/mentoring validation methodologies for clinical trial support in a GLP environment.
Must demonstrate full competency under regulated environment (e.g. GLP, BSL-3/SA).
Ability to work in A/BSL-1, 2, and 3 environments.
Must be eligible to work in the U.S. without employer sponsorship.
As a Federal contractor, Southern Research may be required to comply with a Federal COVID-19 vaccination mandate. In that event, Southern Research will require that all newly hired employees show proof of full COVID vaccination or authorized exemption prior to their start date.

Work Environment & Conditions
This position is in a laboratory environment (A/BSL 1, 2, & 3) and requires the use of personal protective equipment (PPE) including (but not limited to):

Eye protection (Safety glasses and/or full face shield)
Respirator (varies based on tasks and barrier requirements)
Tyvek/scrub suits
Nitrile (or equivalent) gloves (varies based on tasks)
Hearing protection (varies based on tasks)

Immunizations are required for this position and are determined by the study/agent. Some examples include Tetanus, Hepatitis B, Smallpox, Polio, and Influenza.
Physical Demands
This position requires the following physical abilities including (but not limited to):

Performing work with utilizing a computer for extended periods of time.
Sitting for extended periods of time without being able to leave the work area.
Standing for extended periods of time without being able to leave the work area.

Certifications, Licenses & Registrations
No certifications are required; however, training includes Good Laboratory Practices and annual training on safe handling of viruses. Radiation safety training may be required depending upon the assays utilized.